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I also find a small dose of Doxylamine helps hugely and take an eighth of a 50mg dose when I need to.I hope things improve for you soon, my body seems at last to be settling down and I do now feel better than I have for a long time

Reader beware, this is a complex topic, but nonetheless, lets dig into this a bit more, with a look at how MTHFR relates to DNA methylation and the one-carbon pathway